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Questions regarding Finasteride efficiency and Dutasteride usage

bullitnut

bullitnut

4 awesome repairs with SMG
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#1
Ok so it's been said that Fin slow hairloss down and eventually it's supposed to gradually loose it's effectiveness. Is this fact or just hear say. Has anyone on here actually felt their Finasteride isn't working like it used to?
I've been on Fin for over 10 years and it still works, I haven't noticed any major loss of ground since I began. I sometimes think it's not as good as it was when I shed but it seems to return to normal again so things are still pretty good on it tbh.

Has anyone tried Dutasteride due to Fin loosing ground on here?

Has anyone tried both fin and Dutasteride together on different days? Can't see this being worth while myself to due the longer half life of Dutasteride but I've read some stories where people have said it helped?

For those who've tried Dutasteride did they get any sides and do you feel it was worth the switch from Fin?

Just a few random questions sorry
 
Baldingman

Baldingman

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#2
I have been reading that the topical finasteride is proving to be a lot more effective. I think the formula has been changed, making it a stronger dosage. If you lose more hair while taking these medications you could be in for a shocker some years after any surgery.
 
V

Viking

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#3
Whats the difference between the two medications Bullitnut? Baldingman is the topical sold online?
 
bullitnut

bullitnut

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#4
Hi Viking this Article if found pretty much sums up both medications dude.


Finasteride, commonly known on the market as Propecia or Proscar, and Dutasteride, also known as Avodart, both work in the same general way.
Most genetic baldness is the result of a hormone call dihydrotestostrone, or DHT. Both medications act to block DHT production and are in a category of drugs known as 5-alpha reductase inhibitors. Basically, they reduce the effectiveness of the enzyme 5-alpha reductase (5RA) which facilitates the creation of DHT from its precursor testosterone.
By chemically fighting the hormones responsible for baldness, both finasteride and dutasteride have shown significant successes in increasing hair growth. Patients also report very few side effects for both medications.
However, there are some significant differences between the two medications. So why might you choose dutasteride vs. finasteride for hair loss? Is one really better than the other?


Finasteride (Propecia, Proscar)
The first of the two medications to hit the market, finasteride made a near immediate mark by providing fast, unmistakable results.
In a study published by the Journal of American Academy of Dermatology (JAAD),over 2,000 men were given either finasteride or a placebo for two years. A specific patch of hair was monitored regularly for hair loss or hair growth.
At the end of the study, results definitively showed that subjects taking finasteride grew signifcantly more hairs than those taking the placebo. After two years, men taking finasteride saw a growth of, on average, 138 hairs in the scalp area studied. Those taking placebo reported excessive hair loss.
Dutasteride (Avodart)
Though on a smaller scale, studies on dutasteride have demonstrated the drug to be significantly more effective than finasteride at male pattern hair loss. With dutasteride, patients can expect even better results in less time.
According to a 24 week joint study, participants receiving dutasteride saw a growth of 109.6 hairs vs the 75.6 hairs on finasteride users.
The reason for the more powerful results comes from the fact that dutasteride is a more potent inhibitor of the enzyme. Whereas finasteride only blocks Type 2 of the 5 alpha reductase enzyme, dutasteride blocks Type 1 and Type 2.
It is important to note that the makers of dutasteride never pursued studies in hair loss, explaining why hair loss studies of dutasteride were done on much smaller populations than finasteride.

Risks & Side Effects
With substantially better results, this means dutasteride must be the clear winner, right?
Not so fast. With increased potency can come increased risks and side effects.
Though overall side effects for both medications are mild and minimal, dutasteride does report higher levels of impotence or decreased libido, though numbers are low. This 2016 study found that 1.21% of patients using the medication for Androgenic Alopecia reported increased sexual dysfunction. In clinical trials, the side effects reversed once the drug was stopped.
It also has several significant drug interactions with certain medications that treat:
  • HIV
  • Blood pressure
  • Angina
  • Infections
Though similar drug interactions as those seen in dutasteride may be possible, studies have shown no significant interactions with finasteride. Still, always tell your doctor about all medications you are currently taking.
Also, only finasteride has technically been approved by the FDA to treat hair loss. Dutasteride was developed to treat benign prostatic hypertrophy (BPH),also known as an enlarged prostate, though it is sometimes prescribed “off-label” for hair loss.

Another important factor is Dutasteride has a half life of 4 weeks where as Finasteride has a half life of 6-8 hours.

Which Medication is Right for Me?
Overall, both dutasteride and finasteride can be safe and effective hair loss treatments. So how do you know the correct choice for you?
If you are in the early stages of balding and this is your first attempt at combatting hair loss, it’s often best to start off slow rather than bring out the big guns right away. Why raise the risk of side effects if a “milder” medication does the trick? Plus, it’s always better to start with what is FDA approved.
It’s suggested that first-time users with minimal to moderate balding choose finasteride.
However, if you’ve been struggling with hair loss for years, have significant hair loss, or have already tried finasteride with little success, it might be the time for dutasteride.