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Anti ageing medicine in hair restoration - free education and advise

Dr Arvind

Dr Arvind

Valued member
Dear readers,
Anti-ageing medicine/genomic medicine:

As a new field, it holds immense possibilities.
There are a host of beneficial steps one can take at home.

However, please remember, you should consult your doctor if already taking treatments for any disease.
The supplements/ interventions/habits are not medical advice. These are findings with scientific studies and research.
Each day, new findings are pouring in.

It’s exciting times ahead.
You may have heard of Elizabeth Parrish. If not, you may like to google her.
The first human possibly to get gene therapy.

Is she alright? Google please. You can see and hear her talk about her treatments.

While gene therapy still needs time for the general population, simple anti-ageing measures in form of healthy habits may help people losing hair to retain them.
So, what are these measures that you should read about and implement?

Intermittent fasting (eat to live…not the other way round)
Take regular HIIT as an exercise
Hot sauna and cold showers
hyperbaric oxygen
Breathcontrol exercises
hypoxia for HGH secretion
increasing endogenous nitric oxide
consuming dried parsley to reduce CD38 levels and many more practical steps that can be initiated now.


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For a long time, I have been reading about many companies trying or hoping for a cell based hair multiplication.

But, the scientific findings suggest that the alternate path of epigenetics and epigenome modification is a better way forward.

Can pattern baldness be considered ageing of the hair and scalp? - Yes, I think so.

Have medicines that can effect gene expression been discovered/invented? - Yes. They may be 1st generation drugs. But they have been researched in animal models and there is good reason to believe they work in humans. Many people are taking them because they were already being used without us knowing their true benefits.

(Of course, wait for more human trials that are being carried out and more planned in future. Such trials happen in the first place when the researchers have good reason to believe they work.)

I don’t have anything against companies trying to make hair in labs.
But, in my experience, it’s more distant and costly.
Unfortunately, for such companies…and fortunately for less well to do patients, anti-ageing medicine works on a preventive pathway.
Many of the medicines and supplements have already been in use for years or decades.

Moreover, there’s a host of measures that can be discussed and started by people who are not aware of them and which are free. You don’t need to pay a doctor.

It’s a lifestyle modification and improvement method. (Not glamorous like cloning).

I will be glad to help readers understand the often simple concepts that can have a far reaching effect on body and hair. Also, if something can prevent cancer will you not take it or even discuss it?

Why hair?! You may ask this.
Scientists researching anti-ageing medicines wanted to visually see the changes in the organ they were working on, so they chose eye instead of liver.

But what most missed was that hair is the fastest growing organ of our body.
Any change in the inside mileu will show it’s effect on hair.

True enough. The researchers, again without trying as usual, found that the hair growth improved.
You may argue fur growth…but there’s more inputs coming about improvements seen in hair quality, color and thickness when used by humans.
And, good news is that the improvement occurs at the cellular/genetic level.
Fisetin, for example works at gene level to change its expression. NMN works to push more hair into anagen phase.
That’s the correct direction.
People losing hair (more and more hair entering telogen), should try to hold onto their hair.
New and better treatments are on way.

These are not some distant dream.

I am a likely candidate to observe the effects.
I have male pattern hairloss in both sides of my family.
I have been using various anti-ageing interventions since 1985, and haven’t turned bald. And I have never used finasteride/propecia.

There’s an urgent need to bring all information out in open.
It’s not that any one doctor will be profiting from this.
It will be a way to a healthy life which will include better hair and skin.
However, it’s not about botox or similar cosmetic quickfixes.

Starting the anti-ageing journey is an all round effort in improving the way one lives, eats, exercises…

Therefore, I wish to share my experiences and knowledge with all who are interested.


I will take the readers on this fascinating journey of a lifetime indeed.
You are welcome to join.

I look forward to reading a different point of view.


I will talk about the anti-ageing steps individually.

Regards,
Dr Capt Arvind Poswal
 
Dr Arvind

Dr Arvind

Valued member
Can the ageing hair sheath cells be rejuvenated to prevent loss of stem cells?
Probably yes.
We are observing the effects of some of the supplements on hair growth.

Reducing the senescent cell load can positively affect hair.

Will applying or consuming NMN, Fisetin or hyaluronic acid be enough to grow hair?
Most likely not.
But a dna based approach is now available.
As step 1 you should get

Comprehensive full body check up
Full DNA mapping
Biological age testing
These will be a starting point.
Then start all interventions like fasting, use of senolytics and other methods.

At end of 6 months, get the same tests done again. Also take pictures and videos of your scalp/hair once a month to help follow up.

How to identify and target senolytic cells was researched (including for pulmonary fibrosis following Covid)?

The following study shows how periodic administration of senolytic drugs can help.

This has great significance for premature hairloss we are seeing nowadays.
Pattern hairloss maybe genetic but it’s affecting people at an increasingly young age.
It’s not unreasonable to postulate that it’s due to premature ageing.
Our hair being the fastest growing organ will show the effects earliest.



Greying of hair may be the signal for skin ageing.
Melanocytes turn senile and then affect the other cells.

It will be logical to say that we age our organs differently. That’s as true for our heart, liver, kidney, as it’s for our hair.

This premature ageing of the hair has been studied and some interesting facts have come to light about the potential of fisetin and resveratrol.


This leads me to believe that antiageing interventions and supplements have a potential to stop and even reverse pattern hairloss.
Please let me know your thoughts.
Regards,
Dr Capt Arvind Poswal
 
Techno1

Techno1

member
I would be interested to view any patients who try these therapies.
 
Bigmac

Bigmac

Administrator
Staff member
Interesting and certainly not to be dismissed. As well as possibly preventing hair loss, it could reverse or prevent grey hair too.
 
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